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Cells have to sense and to integrate signals, and they have to make decisions, when environmental conditions are changing. We are interested in their decision-making process including protein-DNA interactions defined by transcription factors and their targets around promoters as well as the impact of small RNA regulators which often interfere with target messenger RNAs modulating their translation and degradation.

Combining diverse expertise, we are an inter-disciplinary research team running experiments ranging from small-scale assays in a reaction tube to measurements of global gene expression in a bioreactor, well-defined ODE systems to large-scale data analysis.